Article
The signature of pharmaceutical sensitivity based on ctDNA mutation in eleven cancers.
Experimental biology and medicine (Maywood, N.J.) - 1 Apr 2020
Zhang Shumei, Su Mu, Sun Zhongyi, Lu Haibo, Zhang Yan
Abstract excerpt
IMPACT STATEMENT: Gene mutations are closely related to cancers and drug sensitivity and noninvasive liquid biopsy was used to detect mutations of ctDNA in plasma. In this study, we performed exon sequencing of 416 cancer-related genes for cancer primary tissue and plasma samples of 20 patients in 11 cancers and obtained the comprehensive mutation landscape. We found that liquid biopsy is reliable in place of...
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