Article
Influence of haplotypes, gene expression and soluble levels of L-selectin on the risk of acute coronary syndrome.
Gene - 20 Aug 2017
Sandoval-Pinto Elena, Padilla-Gutiérrez Jorge Ramón, Hernández-Bello Jorge, Martínez-Fernández Diana Emilia, Valdés-Alvarado Emmanuel, Muñoz-Valle José Francisco, Flores-Salinas H E, Valle Yeminia
Abstract excerpt
BACKGROUND: L-selectin gene (SELL) is a candidate gene for the development of acute coronary syndrome (ACS) that contributes to endothelial dysfunction. The -642C>T (rs2205849) and 725C>T (rs2229569) polymorphisms have been associated with changes in gene expression, ligand affinity and increased risk of cardiovascular disease. The aim of this study was to investigate the association between the haplotypes...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
