Influence of haplotypes, gene expression and soluble levels of L-selectin on the risk of acute coronary syndrome.

doi:10.1016/j.gene.2017.05.005

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Article

Influence of haplotypes, gene expression and soluble levels of L-selectin on the risk of acute coronary syndrome.

Gene - 20 Aug 2017

Sandoval-Pinto Elena, Padilla-Gutiérrez Jorge Ramón, Hernández-Bello Jorge, Martínez-Fernández Diana Emilia, Valdés-Alvarado Emmanuel, Muñoz-Valle José Francisco, Flores-Salinas H E, Valle Yeminia

Abstract excerpt

BACKGROUND: L-selectin gene (SELL) is a candidate gene for the development of acute coronary syndrome (ACS) that contributes to endothelial dysfunction. The -642C>T (rs2205849) and 725C>T (rs2229569) polymorphisms have been associated with changes in gene expression, ligand affinity and increased...

Topics

Acute Coronary Syndrome
Aged
Case-Control Studies
Female
Haplotypes
Humans
L-Selectin
Male
Middle Aged
Polymorphism, Single Nucleotide
RNA, Messenger

Source

Open in PubMed

Identifiers

PMID: 28478085
DOI: 10.1016/j.gene.2017.05.005

Genes

SELL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-28478085-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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