Article
Association analysis of polymorphisms in VMAT2 and TMEM106B genes for Parkinson's disease, amyotrophic lateral sclerosis and multiple system atrophy.
Journal of the neurological sciences - 15 Jun 2017
Hu Tao, Chen Yongping, Ou Ruwei, Wei Qianqian, Cao Bei, Zhao Bi, Wu Ying, Song Wei, Chen Xueping, Shang Hui-Fang
Abstract excerpt
BACKGROUND: The vesicular monoamine transporter type 2 (VMAT2) and transmembrane Protein 106B (TMEM106B) were reported to be associated with neurodegenerative diseases. Recent studies found that two polymorphisms (rs363371 and rs363324) in VMAT2 might be a risk factor for Parkinson's disease (PD) in Caucasians, while the two other variants (rs1990622 and rs3173615) in TMEM106B increased the risk for...
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