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Hyaluronan keeps mesenchymal stem cells quiescent and maintains the differentiation potential over time

4 May 2017

Abstract excerpt

Hyaluronan (HA), an abundant polysaccharide found in human bodies, plays a role in the mesenchymal stem cells (MSCs) maintenance. We had previously found that HA prolonged the lifespan, and prevented the cellular aging of murine adipose-derived stromal cells. Recently, we had also summarized the potential pathways associated with HA regulation in human MSCs. In this study, we used the human placenta-derived MSCs...

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PMID: 28474484
DOI: 10.1111/acel.12567

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