Article
Hyaluronic acid enhances proliferation of human amniotic mesenchymal stem cells through activation of Wnt/β-catenin signaling pathway.
Experimental cell research - 15 Jul 2016
Liu Ru-Ming, Sun Ren-Gang, Zhang Ling-Tao, Zhang Qing-Fang, Chen Dai-Xiong, Zhong Jian-Jiang, Xiao Jian-Hui
Abstract excerpt
This study investigated the pro-proliferative effect of hyaluronic acid (HA) on human amniotic mesenchymal stem cells (hAMSCs) and the underlying mechanisms. Treatment with HA increased cell population growth in a dose- and time-dependent manner. Analyses by flow cytometry and immunocytochemistry revealed that HA did not change the cytophenotypes of hAMSCs. Additionally, the osteogenic, chondrogenic, and...
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