Article
MRI and biomechanics multidimensional data analysis reveals R2 -R1ρ as an early predictor of cartilage lesion progression in knee osteoarthritis.
Journal of magnetic resonance imaging : JMRI - 1 Jan 2018
Pedoia Valentina, Haefeli Jenny, Morioka Kazuhito, Teng Hsiang-Ling, Nardo Lorenzo, Souza Richard B, Ferguson Adam R, Majumdar Sharmila
Abstract excerpt
PURPOSE: To couple quantitative compositional MRI, gait analysis, and machine learning multidimensional data analysis to study osteoarthritis (OA). OA is a multifactorial disorder accompanied by biochemical and morphological changes in the articular cartilage, modulated by skeletal biomechanics and gait. While we can now acquire detailed information about the knee joint structure and function, we are not yet able...
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