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Article

The Angiopoietin-Tie2 Signaling Axis in Systemic Inflammation

2 May 2017

Abstract excerpt

Systemic inflammation is a hallmark of commonly encountered diseases ranging from bacterial sepsis to sterile syndromes such as major trauma. Derangements in the host vasculature contribute to the cardinal manifestations of sepsis in profound ways. Recent studies of control pathways regulating the vascular endothelium have illuminated how this single cell layer toggles between quiescence and activation to affect...

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Identifiers

PMID: 28465380
DOI: 10.1681/asn.2017010069

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