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Article

Association of regulatory TPH2 polymorphisms with higher reduction in depressive symptoms in children and adolescents treated with fluoxetine.

Progress in neuro-psychopharmacology & biological psychiatry - 3 Jul 2017

Gassó Patricia, Rodríguez Natalia, Boloc Daniel, Blázquez Ana, Torres Teresa, Gortat Ana, Plana Maria Teresa, Lafuente Amalia, Mas Sergi, Arnaiz Joan Albert, Lázaro Luisa

Abstract excerpt

Genetic variability related to the brain serotonergic system has a significant impact on both the susceptibility to psychiatric disorders, such as major depressive disorder (MDD), and the response to antidepressant drugs, such as fluoxetine. TPH2 is one of the most important serotonergic candidate genes in selective serotonin reuptake inhibitors (SSRIs) pharmacogenetic studies. The aim of the present study was to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28456685
DOI: 10.1016/j.pnpbp.2017.04.031

Genes

TPH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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