Article
Impact of RNA structure on ZFP36L2 interaction with luteinizing hormone receptor mRNA.
RNA (New York, N.Y.) - 1 Aug 2017
Ball Christopher B, Solem Amanda C, Meganck Rita M, Laederach Alain, Ramos Silvia B V
Abstract excerpt
ZFP36L2 (L2) destabilizes AU-rich element (ARE)-containing transcripts and has been implicated in female fertility. We have shown that only one of three putative AREs within the 3' UTR of murine luteinizing hormone receptor mRNA, ARE2197 (UAUUUAU), is capable of interacting with L2. To assess whether structural elements of ARE2197 could explain this unique binding ability, we performed whole-transcript SHAPE-MaP...
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