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Article

Computation of ancestry scores with mixed families and unrelated individuals.

Biometrics - 1 Mar 2018

Zhou Yi-Hui, Marron James S, Wright Fred A

Abstract excerpt

The issue of robustness to family relationships in computing genotype ancestry scores such as eigenvector projections has received increased attention in genetic association, and is particularly challenging when sets of both unrelated individuals and closely related family members are included. The current standard is to compute loadings (left singular vectors) using unrelated individuals and to compute projected...

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PMID: 28452052
DOI: 10.1111/biom.12708
PMCID: PMC6069602

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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