Article
Key rates for the grades and transformation ability of glioma: model simulations and clinical cases.
Journal of neuro-oncology - 1 Jun 2017
Scribner Elizabeth, Hackney James R, Machemehl Hannah C, Afiouni Reina, Patel Krishna R, Fathallah-Shaykh Hassan M
Abstract excerpt
Tumor progression to higher grade is a fundamental property of cancer. The malignant advancement of the pathological features may either develop during the later stages of cancer growth (natural evolution) or it may necessitate new mutations or molecular events that alter the rates of growth, dispersion, or neovascularization (transformation). Here, we model the pathological and radiological features of grades...
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