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Article

Comparative pharmacology of a new recombinant FSH expressed by a human cell line

27 Apr 2017

Abstract excerpt

Recombinant FSH proteins are important therapeutic agents for the treatment of infertility, including follitropin alfa expressed in Chinese Hamster Ovary (CHO) cells and, more recently, follitropin delta expressed in the human cell line PER.C6. These recombinant FSH proteins have distinct glycosylation, and have distinct pharmacokinetic and pharmacodynamic profiles in women. Comparative experiments demonstrated...

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PMID: 28450423
DOI: 10.1530/ec-17-0067

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