Article
Trafficking of the follitropin receptor.
Methods in enzymology - 1 Jan 2013
Ulloa-Aguirre Alfredo, Dias James A, Bousfield George, Huhtaniemi Ilpo, Reiter Eric
Abstract excerpt
The follitropin or follicle-stimulating hormone receptor (FSHR) belongs to a highly conserved subfamily of the G protein-coupled receptor (GPCR) superfamily and is mainly expressed in specific cells in the gonads. As any other GPCR, the newly synthesized FSHR has to be correctly folded and processed in order to traffic to the cell surface plasma membrane and interact with its cognate ligand. In this chapter, we...
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