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Article

Hereditary spastic paraplegia: More than an upper motor neuron disease.

Revue neurologique - 1 May 2017

Parodi L, Fenu S, Stevanin G, Durr A

Abstract excerpt

Hereditary spastic paraplegias (HSPs) are a group of rare inherited neurological diseases characterized by extreme heterogeneity in both their clinical manifestations and genetic backgrounds. Based on symptoms, HSPs can be divided into pure forms, presenting with pyramidal signs leading to lower-limb spasticity, and complex forms, when additional neurological or extraneurological symptoms are detected. The...

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Amyotrophic Lateral Sclerosis
Heat-Shock Proteins
Hereditary Neurological Disorders
Motor Neuron Disease
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neurogenetic and Muscular Disorders Research

Neurological diseases and metabolism

Spastic Paraplegia, Hereditary

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PMID: 28449883
DOI: 10.1016/j.neurol.2017.03.034

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