Prognostic Evaluation of Epidermal Growth Factor Receptor (EGFR) Genotype and Phenotype Parameters in Triple-negative Breast Cancers.

doi:10.21873/cgp.20030

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Prognostic Evaluation of Epidermal Growth Factor Receptor (EGFR) Genotype and Phenotype Parameters in Triple-negative Breast Cancers.

Cancer genomics & proteomics - 1 Jan 2000

Levva Sofia, Kotoula Vassiliki, Kostopoulos Ioannis, Manousou Kyriaki, Papadimitriou Christos, Papadopoulou Kyriaki, Lakis Sotiris, Koukoulias Kyriakos, Karavasilis Vasilios, Pentheroudakis George, Balassi Eufemia, Zagouri Flora, Kaklamanos Ioannis G, Pectasides Dimitrios, Razis Evangelia, Aravantinos Gerasimos, Papakostas Pavlos, Bafaloukos Dimitrios, Rallis Grigorios, Gogas Helen, Fountzilas George

Abstract excerpt

BACKGROUND: Epidermal growth factor receptor (EGFR) aberrations have been implicated in the pathogenesis of triple-negative breast cancer (TNBC) but their impact on prognosis and, therefore, druggability, remain controversial. Herein, we studied EGFR aberrations at different molecular levels and assessed their prognostic impact in patients with operable TNBC treated with adjuvant anthracycline-based chemotherapy....

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Identifiers

PMID: 28446533
DOI: 10.21873/cgp.20030
PMCID: PMC5420819

Genes

EGFR

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