Article
EGFR genomic alterations in cancer: prognostic and predictive values.
Frontiers in bioscience (Elite edition) - 1 Jun 2011
Bronte Giuseppe, Terrasi Marianna, Rizzo Sergio, Sivestris Nicola, Ficorella Corrado, Cajozzo Massimo, Di Gaudio Francesca, Gulotta Gaspare, Siragusa Sergio, Gebbia Nicola, Russo Antonio
Abstract excerpt
The role of EGFR in cancer development and progression has been recognized for long time in a variety of human malignancies including lung, head and neck, colon, breast, ovary and glioma. Recently its role as a target of antineoplastic agents has also been identified and a variety of EGFR-targeted drugs is already being used in a clinical setting and others are at present under investigation. Many data involving...
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