Article
Triple negative breast cancer: molecular profiling and prognostic impact in adjuvant anthracycline-treated patients.
Breast cancer research and treatment - 1 Sept 2008
Tan David S P, Marchió Caterina, Jones Robin L, Savage Kay, Smith Ian E, Dowsett Mitch, Reis-Filho Jorge S
Abstract excerpt
BACKGROUND: We analysed the clinical features, distribution of basal markers, prevalence of oncogene amplification, and outcome of triple negative (TN) compared to those of non-TN cancers in a series of adjuvant-anthracycline treated breast cancer patients. METHODS: We examined the prognostic impact of the TN and BL phenotype in 245 breast cancer patients uniformly treated with adjuvant anthracycline-based...
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