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Article

Adipose-derived mesenchymal stem cells modulate CD14++CD16+ expression on monocytes from sepsis patients in vitro via prostaglandin E2.

Stem cell research & therapy - 26 Apr 2017

Qiu Guanguan, Zheng Guoping, Ge Menghua, Huang Lanfang, Tong Haijiang, Chen Ping, Lai Dengming, Hu Yaoqin, Cheng Baoli, Shu Qiang, Xu Jianguo

Abstract excerpt

BACKGROUND: Mesenchymal stem cells (MSCs) have been shown to reduce sepsis-induced inflammation and improve survival in mouse models of sepsis. CD16+ monocytes are proinflammatory and abundant in inflammatory conditions such as sepsis. The primary objective in this exploratory study was to determine the effects of adipose-derived MSCs (ASCs) on three subsets of monocytes from sepsis patients in vitro and to...

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Identifiers

PMID: 28446249
DOI: 10.1186/s13287-017-0546-x
PMCID: PMC5406890

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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