Functional genetic variants within the SIRT2 gene promoter in type 2 diabetes mellitus.

doi:10.1016/j.diabres.2018.01.012

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Article

Functional genetic variants within the SIRT2 gene promoter in type 2 diabetes mellitus.

Diabetes research and clinical practice - 1 Mar 2018

Liu Tingting, Yang Wentao, Pang Shuchao, Yu Shipeng, Yan Bo

Abstract excerpt

AIMS: Type 2 diabetes mellitus (T2D) is a common and complex metabolic diseases caused by interactions between environmental and genetic factors. Genome-wide association studies have identified more than 80 common genetic variants for T2D, which account for only ∼10% of the heritability of T2D cases. SIRT2, a member of NAD(+)-dependent class III deacetylases, is involved in genomic stability, metabolism,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29371109
DOI: 10.1016/j.diabres.2018.01.012

Genes

SIRT2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.