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Article

DNA methylome analysis reveals distinct epigenetic patterns of ascending aortic dissection and bicuspid aortic valve.

Cardiovascular research - 1 May 2017

Pan Sun, Lai Hao, Shen Yiru, Breeze Charles, Beck Stephan, Hong Tao, Wang Chunsheng, Teschendorff Andrew E

Abstract excerpt

AIMS: Epigenetics may mediate the effects of environmental risk factors on disease, including heart disease. Thus, measuring the DNA methylome offers the opportunity to identify novel disease biomarkers and novel insights into disease mechanisms. The DNA methylation landscape of ascending aortic dissection (AD) and bicuspid aortic valve (BAV) with aortic aneurysmal dilatation remain uncharacterized. The present...

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Identifiers

PMID: 28444195
DOI: 10.1093/cvr/cvx050

Genes

RARA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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