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MicroRNA and mRNA Dysregulation in Astrocytes Infected with Zika Virus

14 Oct 2017

Abstract excerpt

The Zika virus (ZIKV) epidemic is an ongoing public health concern. ZIKV is a flavivirus reported to be associated with microcephaly, and recent work in animal models demonstrates the ability of the virus to cross the placenta and affect fetal brain development. Recent findings suggest that the virus preferentially infects neural stem cells and thereby deregulates gene expression, cell cycle progression, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29036922
DOI: 10.3390/v9100297

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