Article
Extensive diversity in circadian regulation of plasma lipids and evidence for different circadian metabolic phenotypes in humans.
Proceedings of the National Academy of Sciences of the United States of America - 27 Aug 2013
Chua Eric Chern-Pin, Shui Guanghou, Lee Ivan Tian-Guang, Lau Pauline, Tan Luuan-Chin, Yeo Sing-Chen, Lam Buu Duyen, Bulchand Sarada, Summers Scott A, Puvanendran Kathiravelu, Rozen Steven G, Wenk Markus R, Gooley Joshua J
Abstract excerpt
The circadian system regulates daily rhythms in lipid metabolism and adipose tissue function. Although disruption of circadian clock function is associated with negative cardiometabolic end points, very little is known about interindividual variation in circadian-regulated metabolic pathways. Here, we used targeted lipidomics-based approaches to profile the time course of 263 lipids in blood plasma in 20 healthy...
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