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Article

Lipoprotein Particle Profiles Mark Familial and Sporadic Human Longevity

20 Dec 2006

Abstract excerpt

BACKGROUND: Genetic and biochemical studies have indicated an important role for lipid metabolism in human longevity. Ashkenazi Jewish centenarians and their offspring have large low-density lipoprotein (LDL) and high-density lipoprotein (HDL) particles as compared with control individuals. This profile also coincided with a lower prevalence of disease. Here, we investigate whether this observation can be...

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PMID: 17194192
DOI: 10.1371/journal.pmed.0030495

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