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Is HLA the cause of the high incidence of type 1 diabetes in the Canary Islands? Results from the Type 1 Diabetes Genetics Consortium (T1DGC).

Endocrinologia, diabetes y nutricion - 1 Mar 2017

Santana Del Pino Angelo, Medina-Rodríguez Nathan, Hernández-García Marta, Nóvoa-Mogollón Francisco J, Wägner Ana M

Abstract excerpt

INTRODUCTION: Incidence of childhood-onset type 1 diabetes mellitus in the Canary Islands is the highest reported so far in Spain, and among the highest worldwide. The HLA region accounts for approximately half the genetic risk of type 1 diabetes. Our aim was to assess distribution of high-risk and protective HLA haplotypes in the Canarian families included in the T1DGC, as compared to the rest of Spain. METHODS:...

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Identifiers

PMID: 28440753
DOI: 10.1016/j.endinu.2016.12.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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