Article
Both Hepatitis C Virus-Specific T Cell Responses and IL28B rs12979860 Single-Nucleotide Polymorphism Genotype Influence Antihepatitis C Virus Treatment Outcome in Patients with Chronic Hepatitis C.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Jun 2017
Benito José M, García-Samaniego Javier, García Marcial, Madejón Antonio, Martín-Carbonero Luz, Cabello Alfonso, Álvarez Beatriz, Górgolas Miguel, Rallón Norma
Abstract excerpt
Despite new treatments for hepatitis C virus (HCV) infection, IFNα-based regimens still have clinical relevance in special populations of patients and remain the only therapeutic option for many patients. We sought to elucidate the interplay between two relevant factors (IL28B polymorphism and T cell immune responses) involved in the outcome of this therapy in HCV-infected patients. We evaluated 38 patients...
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