Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial transcription factor A (TFAM) is upregulated in glioma

12 Apr 2017

Abstract excerpt

Mitochondrial transcription factor A (TFAM), which was initially discovered as a transcription factor for mitochondrial DNA, has known to be critical for the regulation of mitochondrial DNA. However the possible involvement of TFAM in cancer is largely unknown. In this study, we have provided some evidence that TFAM may have a potential role in brain tumor. Western blot analysis with anti‑TFAM antibody indicated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP Synthase and ATPases Research
Share to Glioma Diagnosis and Treatment
Share to Mitochondrial Function and Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28440425
DOI: 10.3892/mmr.2017.6467

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial transcription factor A (TFAM) is upregulated in gliomaPMID 28440425Read ↗

Mitochondrial RNA modification-based signature to predict prognosis of lower grade glioma: a multi-omics exploration and verification studySemantic proximity Read ↗

Mitochondrial Genome Regulator TFAM Modulates Head and Neck Tumorigenesis Through Activation of Intracellular Metabolic Reprogramming and Oncogenic EffectorsSemantic proximity Read ↗

The FDX1 methylation regulatory mechanism in the malignant phenotype of glioma.Semantic proximity Read ↗

<p class="MDPI12titleori1" style="mso-line-height-alt: 14.0pt;"><span style="mso-bidi-font-size: 18.0pt;">A Coordinated Mitochondrial Genome Program Predicts Improved Outcome in Lower-Grade GliomaSemantic proximity Read ↗

Mitochondrial genome and its regulator TFAM modulates head and neck tumourigenesis through intracellular metabolic reprogramming and activation of oncogenic effectors.Semantic proximity Read ↗

The new oncogene transmembrane protein 60 is a potential therapeutic target in gliomaSemantic proximity Read ↗

Human mitochondrial transcription factor A possesses multiple subcellular targeting signals.Semantic proximity Read ↗

High leukocyte mitochondrial DNA content contributes to poor prognosis in glioma patients through its immunosuppressive effectSemantic proximity Read ↗

The importance of mitochondria in the tumourigenic phenotype: gliomas as the paradigm (review).Semantic proximity Read ↗

p53 increase mitochondrial copy number via up-regulation of mitochondrial transcription factor A in colorectal cancerSemantic proximity Read ↗

Repression of the expression of proinflammatory genes by mitochondrial transcription factor A is linked to its alternative splicing regulation in human lung epithelial cellsSemantic proximity Read ↗

Mitochondrial DNA depletion and its correlation with TFAM, TFB1M, TFB2M and POLG in human diffusely infiltrating astrocytomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.