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Article

The FDX1 methylation regulatory mechanism in the malignant phenotype of glioma.

Genomics - 1 Mar 2023

Guowei Li, Xiufang Lu, Qianqian Xu, Yanping Jin

Abstract excerpt

To explore FDX1 methylation as a regulatory mechanism in the malignant phenotype of glioma, we screened for pathways involved through bioinformatic analysis, then proceeded with RIP and cell models to verify the regulation of RNAs and mitophagy. We chose Clone and Transwell assays to evaluate the malignant phenotype of glioma cells. MMP was detected by flow cytometry and mitochondrial morphology was observed by...

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PMID: 36889365
DOI: 10.1016/j.ygeno.2023.110601

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