Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High leukocyte mitochondrial DNA content contributes to poor prognosis in glioma patients through its immunosuppressive effect

28 May 2015

Abstract excerpt

BACKGROUND: Epidemiological studies have indicated significant associations of leukocyte mitochondrial DNA (mtDNA) copy number with risk of several malignancies, including glioma. However, whether mtDNA content can predict the clinical outcome of glioma patients has not been investigated. METHODS: The mtDNA content of peripheral blood leukocytes from 336 glioma patients was examined using a real-time PCR-based...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ferroptosis and cancer prognosis
Share to Glioma Diagnosis and Treatment
Share to Mitochondrial Function and Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26022928
DOI: 10.1038/bjc.2015.184

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High leukocyte mitochondrial DNA content contributes to poor prognosis in glioma patients through its immunosuppressive effectPMID 26022928Read ↗

Leukocyte mitochondrial DNA content: a novel biomarker associated with prognosis and therapeutic outcome in colorectal cancerSemantic proximity Read ↗

Novel prognostic features and personalized treatment strategies for mitochondria-related genes in glioma patientsSemantic proximity Read ↗

Mitochondrial DNA Alterations in Glioblastoma and Current Therapeutic Targets.Semantic proximity Read ↗

Mitochondrial DNA Alterations in Glioblastoma (GBM).Semantic proximity Read ↗

Somatic mitochondrial DNA mutations in different grades of glioma.Semantic proximity Read ↗

Association between leukocyte telomere length and glioma risk: a case-control studySemantic proximity Read ↗

Leukocyte telomere length: a novel biomarker to predict the prognosis of glioma patientsSemantic proximity Read ↗

Association between mitochondrial DNA content in leukocytes and colorectal cancer riskSemantic proximity Read ↗

Glioma grade and mortality in relation to sequence variation in the mitochondrial genome.Semantic proximity Read ↗

Mitochondrial transcription factor A (TFAM) is upregulated in gliomaSemantic proximity Read ↗

Mitochondrial DNA depletion and its correlation with TFAM, TFB1M, TFB2M and POLG in human diffusely infiltrating astrocytomasSemantic proximity Read ↗

Involvement of poly(ADP-ribose) polymerase-1 in Chinese patients with glioma: a potential target for effective patient care.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.