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Article

Observation of ice-like water layers at an aqueous protein surface.

Proceedings of the National Academy of Sciences of the United States of America - 16 Dec 2014

Meister Konrad, Strazdaite Simona, DeVries Arthur L, Lotze Stephan, Olijve Luuk L C, Voets Ilja K, Bakker Huib J

Abstract excerpt

We study the properties of water at the surface of an antifreeze protein with femtosecond surface sum frequency generation spectroscopy. We find clear evidence for the presence of ice-like water layers at the ice-binding site of the protein in aqueous solution at temperatures above the freezing point. Decreasing the temperature to the biological working temperature of the protein (0 °C to -2 °C) increases the...

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Identifiers

PMID: 25468976
DOI: 10.1073/pnas.1414188111
PMCID: PMC4273357

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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