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Article

Identifying new susceptibility genes on dopaminergic and serotonergic pathways for the framing effect in decision-making.

Social cognitive and affective neuroscience - 1 Sept 2017

Gao Xiaoxue, Liu Jinting, Gong Pingyuan, Wang Junhui, Fang Wan, Yan Hongming, Zhu Lusha, Zhou Xiaolin

Abstract excerpt

The framing effect refers the tendency to be risk-averse when options are presented positively but be risk-seeking when the same options are presented negatively during decision-making. This effect has been found to be modulated by the serotonin transporter gene (SLC6A4) and the catechol-o-methyltransferase gene (COMT) polymorphisms, which are on the dopaminergic and serotonergic pathways and which are associated...

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Source

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Identifiers

PMID: 28431168
DOI: 10.1093/scan/nsx062
PMCID: PMC5629826

Genes

COMT
DDC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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