Article
Interaction between PPAR γ and SORL1 gene with Late-Onset Alzheimer's disease in Chinese Han Population.
Oncotarget - 18 Jul 2017
Zhang Hui, Zheng Wei, Hua Linlin, Wang Yutong, Li Jinfeng, Bai Hongying, Wang Shanshan, Du Mingyao, Ma Xuelian, Xu Chunyang, Li Xiaodong, Gong Bin, Wang Yunliang
Abstract excerpt
AIMS: To investigate the impact of sortilin-related receptor 1 gene 1 (SORL1) and peroxisome proliferator activated receptor gamma (PPAR G) gene single nucleotide polymorphisms (SNPs), gene- gene and gene- environment interactions and haplotype on late-onset Alzheimer's disease (LOAD) risk. METHODS: Hardy-Weinberg equilibrium (HWE), haplotype analysis and pairwise linkage disequilibrium (LD) analysis were...
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