GNPAT rs11558492 is not a Major Modifier of Iron Status: Study of Italian Hemochromatosis Patients and Blood Donors.

doi:10.5604/16652681.1235489

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Article

GNPAT rs11558492 is not a Major Modifier of Iron Status: Study of Italian Hemochromatosis Patients and Blood Donors.

Annals of hepatology - 1 Jan 2000

Greni Federico, Valenti Luca, Mariani Raffaella, Pelloni Irene, Rametta Raffaela, Busti Fabiana, Ravasi Giulia, Girelli Domenico, Fargion Silvia, Galimberti Stefania, Piperno Alberto, Pelucchi Sara

Abstract excerpt

BACKGROUND AND AIM: HFE-related Hemochromatosis (HH) is characterized by marked phenotype heterogeneity, probably due to the combined action of acquired and genetic factors. Among them, GNPAT rs11558492 was proposed as genetic modifier of iron status, but results are still controversial. To shed light on these discrepancies, we genotyped 298 Italian p.C282Y homozygotes and 169 healthy controls. MATERIAL AND...

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Identifiers

PMID: 28425416
DOI: 10.5604/16652681.1235489

Genes

GNPAT
HFE
MAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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