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Article

Detecting rare haplotype-environment interaction with logistic Bayesian LASSO.

Genetic epidemiology - 1 Jan 2014

Biswas Swati, Xia Shuang, Lin Shili

Abstract excerpt

Two important contributors to missing heritability are believed to be rare variants and gene-environment interaction (GXE). Thus, detecting GXE where G is a rare haplotype variant (rHTV) is a pressing problem. Haplotype analysis is usually the natural second step to follow up on a genomic region that is implicated to be associated through single nucleotide variants (SNV) analysis. Further, rHTV can tag associated...

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PMID: 24272913
DOI: 10.1002/gepi.21773
PMCID: PMC4174302

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