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Article

MR elastography detection of early viscoelastic response of the murine hippocampus to amyloid β accumulation and neuronal cell loss due to Alzheimer's disease.

Journal of magnetic resonance imaging : JMRI - 1 Jan 2018

Munder Tonia, Pfeffer Anna, Schreyer Stefanie, Guo Jing, Braun Juergen, Sack Ingolf, Steiner Barbara, Klein Charlotte

Abstract excerpt

PURPOSE: To investigate in vivo viscoelastic parameters related to early histopathological changes in the hippocampus and the cortex in early, preclinical Alzheimer's disease (AD) stages. MATERIALS AND METHODS: Magnetic resonance elastography (MRE) was applied to female APP23 mice, an established transgenic mouse model of AD, at three different stages early in disease progression. To investigate the potential...

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PMID: 28422391
DOI: 10.1002/jmri.25741

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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