Article
Age-dependent impairment of somatosensory response in the amyloid precursor protein 23 transgenic mouse model of Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 10 Sept 2003
Mueggler Thomas, Baumann Diana, Rausch Martin, Staufenbiel Matthias, Rudin Markus
Abstract excerpt
Quantitative functional magnetic resonance imaging was applied to characterize brain function in amyloid precursor protein 23 (APP23) transgenic mice, which reproduce the neuropathological alterations associated with Alzheimer's disease. Electrical stimulation of the paw led to cerebral blood vol...
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