Article
MicroRNA Metabolism and Dysregulation in Amyotrophic Lateral Sclerosis.
Molecular neurobiology - 1 Mar 2018
Rinchetti Paola, Rizzuti Mafalda, Faravelli Irene, Corti Stefania
Abstract excerpt
MicroRNAs (miRNAs) are a subset of endogenous, small, non-coding RNA molecules involved in the post-transcriptional regulation of eukaryotic gene expression. Dysregulation in miRNA-related pathways in the central nervous system (CNS) is associated with severe neuronal injury and cell death, which can lead to the development of neurodegenerative disorders, such as amyotrophic lateral sclerosis (ALS). ALS is a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
