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The Biogenesis of miRNAs and Their Role in the Development of Amyotrophic Lateral Sclerosis

7 Feb 2022

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects upper and lower motor neurons. As there is no effective treatment for ALS, it is particularly important to screen key gene therapy targets. The identifications of microRNAs (miRNAs) have completely changed the traditional view of gene regulation. miRNAs are small noncoding single-stranded RNA molecules involved in the regulation of...

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PMID: 35159383
DOI: 10.3390/cells11030572

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