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Article

Identification of putative second genetic hits in schizophrenia carriers of high-risk copy number variants and resequencing in additional samples.

European archives of psychiatry and clinical neuroscience - 1 Sept 2018

Rodríguez-López Julio, Sobrino Beatriz, Amigo Jorge, Carrera Noa, Brenlla Julio, Agra Santiago, Paz Eduardo, Carracedo Ángel, Páramo Mario, Arrojo Manuel, Costas Javier

Abstract excerpt

Copy number variants (CNVs) conferring risk of schizophrenia present incomplete penetrance, suggesting the existence of second genetic hits. Identification of second hits may help to find genes with rare variants of susceptibility to schizophrenia. The aim of this work was to search for second hits of moderate/high risk in schizophrenia carriers of risk CNVs and resequencing of the relevant genes in additional...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28421333
DOI: 10.1007/s00406-017-0799-5

Genes

SYNJ1
BFAR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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