Article
RICTOR polymorphisms affect efficiency of platinum-based chemotherapy in Chinese non-small-cell lung cancer patients.
Pharmacogenomics - 1 Oct 2016
Wang Shiming, Song Xiao, Li Xiaoying, Zhao Xueying, Chen Hongyan, Wang Jiucun, Wu Junjie, Gao Zhiqiang, Qian Ji, Han Baohui, Bai Chunxue, Li Qiang, Lu Daru
Abstract excerpt
AIM: We investigated the association between RICTOR polymorphisms and clinical outcomes of platinum-based chemotherapy for Chinese non-small-cell lung cancer patients. MATERIALS & METHODS: Ten tag SNPs were genotyped in 1004 patients to assess their association with clinical benefit, overall survival, progression-free survival, gastrointestinal toxicity, neutropenia, anemia and thrombocytopenia. RESULTS:...
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