Article
Prognostic Relevance of Histomolecular Classification of Diffuse Adult High-Grade Gliomas with Necrosis.
Brain pathology (Zurich, Switzerland) - 1 Jul 2015
Figarella-Branger Dominique, Mokhtari Karima, Colin Carole, Uro-Coste Emmanuelle, Jouvet Anne, Dehais Caroline, Carpentier Catherine, Villa Chiara, Maurage Claude-Alain, Eimer Sandrine, Polivka Marc, Vignaud Jean-Michel, Laquerriere Annie, Sevestre Henri, Lechapt-Zalcman Emmanuelle, Quintin-Roué Isabelle, Aubriot-Lorton Marie-Hélène, Diebold Marie-Danièle, Viennet Gabriel, Adam Clovis, Loussouarn Delphine, Michalak Sophie, Rigau Valérie, Heitzmann Anne, Vandenbos Fanny, Forest Fabien, Chiforeanu Danchristian, Tortel Marie-Claire, Labrousse François, Chenard Marie-Pierre, Nguyen Anh Tuan, Varlet Pascale, Kemeny Jean Louis, Levillain Pierre-Marie, Cazals-Hatem Dominique, Richard Pomone, Delattre Jean-Yves
Abstract excerpt
Diffuse adult high-grade gliomas (HGGs) with necrosis encompass anaplastic oligodendrogliomas (AOs) with necrosis (grade III), glioblastomas (GBM, grade IV) and glioblastomas with an oligodendroglial component (GBMO, grade IV). Here, we aimed to search for prognostic relevance of histological classification and molecular alterations of these tumors. About 210 patients were included (63 AO, 56 GBM and 91 GBMO)....
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