Article
1p/19q codeletion and IDH1/2 mutation identified a subtype of anaplastic oligoastrocytomas with prognosis as favorable as anaplastic oligodendrogliomas.
Neuro-oncology - 1 Jun 2013
Jiang Haihui, Ren Xiaohui, Cui Xiangli, Wang Junmei, Jia Wenqing, Zhou Zhiming, Lin Song
Abstract excerpt
BACKGROUND: Anaplastic astrocytoma (AA), anaplastic oligoastrocytoma (AOA), and anaplastic oligodendroglioma (AO) are the major histological subtypes of World Health Organization grade III gliomas. More evidence suggests that AOA is unlikely to be a distinct entity, and re-evaluation of this issue has been recommended. In this study, we divided AOA into 2 subgroups, according to molecular biomarkers, and compared...
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