Article
A feasibility study of returning clinically actionable somatic genomic alterations identified in a research laboratory.
Oncotarget - 27 Jun 2017
Arango Natalia Paez, Brusco Lauren, Mills Shaw Kenna R, Chen Ken, Eterovic Agda Karina, Holla Vijaykumar, Johnson Amber, Litzenburger Beate, Khotskaya Yekaterina B, Sanchez Nora, Bailey Ann, Zheng Xiaofeng, Horombe Chacha, Kopetz Scott, Farhangfar Carol J, Routbort Mark, Broaddus Russell, Bernstam Elmer V, Mendelsohn John, Mills Gordon B, Meric-Bernstam Funda
Abstract excerpt
PURPOSE: Molecular profiling performed in the research setting usually does not benefit the patients that donate their tissues. Through a prospective protocol, we sought to determine the feasibility and utility of performing broad genomic testing in the research laboratory for discovery, and the utility of giving treating physicians access to research data, with the option of validating actionable alterations in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.