Article
Data resources for the identification and interpretation of actionable mutations by clinicians.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 May 2017
Prawira A, Pugh T J, Stockley T L, Siu L L
Abstract excerpt
Following initial characterization of the reference human genome, initiatives have evolved worldwide to identify genomic aberrations in cancer with the aim of deriving diagnostic, prognostic and predictive information. However, the functional and clinical relevance of many somatic variants in cancer are presently unknown and there is no consensus definition of 'actionability' for genomic aberrancies. Therefore,...
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