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Article

The epigenetic mechanism for discordance of autoimmunity in monozygotic twins.

Journal of autoimmunity - 1 Sept 2017

Xiang Zhongyuan, Yang Yuanqing, Chang Christopher, Lu Qianjin

Abstract excerpt

Monozygotic twins share an identical DNA sequence but are not truly "identical". In fact, when it comes to health and disease, they may often display some level of phenotypic discordance. The cause of this discordance is often unknown. Epigenetic modifications such as DNA methylation, histone modification, and microRNAs-mediated regulation regulate gene expression and are sensitive to external stimuli. These...

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Identifiers

PMID: 28412046
DOI: 10.1016/j.jaut.2017.04.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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