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Article

Increased DNA methylation variability in rheumatoid arthritis-discordant monozygotic twins.

Genome medicine - 4 Sept 2018

Webster Amy P, Plant Darren, Ecker Simone, Zufferey Flore, Bell Jordana T, Feber Andrew, Paul Dirk S, Beck Stephan, Barton Anne, Williams Frances M K, Worthington Jane

Abstract excerpt

BACKGROUND: Rheumatoid arthritis is a common autoimmune disorder influenced by both genetic and environmental factors. Epigenome-wide association studies can identify environmentally mediated epigenetic changes such as altered DNA methylation, which may also be influenced by genetic factors. To investigate possible contributions of DNA methylation to the aetiology of rheumatoid arthritis with minimum confounding...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30176915
DOI: 10.1186/s13073-018-0575-9
PMCID: PMC6122744

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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