Article
Cerebral and muscle microvascular oxygenation in children with sickle cell disease: Influence of hematology, hemorheology and vasomotion.
Blood cells, molecules & diseases - 1 Jun 2017
Charlot Keyne, Antoine-Jonville Sophie, Moeckesch Berenike, Jumet Stéphane, Romana Marc, Waltz Xavier, Divialle-Doumdo Lydia, Hardy-Dessources Marie-Dominique, Petras Marie, Tressières Benoît, Tarer Vanessa, Hue Olivier, Etienne-Julan Maryse, Connes Philippe
Abstract excerpt
The present study investigated cerebral and muscle hemoglobin oxygen saturation (tissue oxygen index, TOI) in children with sickle cell anemia (SS), sickle cell hemoglobin C disease (SC) and healthy children (AA). TOI was measured by near-infrared spectroscopy (NIRS) and spectral analysis of the TOI variability was used to assess flowmotion and vasomotion. Arterial oxyhemoglobin saturation (SpO2), hemorheological...
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