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Article

Inherited variants in genes somatically mutated in thyroid cancer.

PloS one - 1 Jan 2017

Campo Chiara, Köhler Aleksandra, Figlioli Gisella, Elisei Rossella, Romei Cristina, Cipollini Monica, Bambi Franco, Hemminki Kari, Gemignani Federica, Landi Stefano, Försti Asta

Abstract excerpt

BACKGROUND: Tumour suppressor genes when mutated in the germline cause various cancers, but they can also be somatically mutated in sporadic tumours. We hypothesized that there may also be cancer-related germline variants in the genes commonly mutated in sporadic well-differentiated thyroid cancer (WDTC). METHODS: We performed a two-stage case-control association study with a total of 2214 cases and 2108 healthy...

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PMID: 28410400
DOI: 10.1371/journal.pone.0174995
PMCID: PMC5391920

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APC
GNAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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