Article
Genetic alterations in seborrheic keratoses.
Oncotarget - 30 May 2017
Heidenreich Barbara, Denisova Evygenia, Rachakonda Sivaramakrishna, Sanmartin Onofre, Dereani Timo, Hosen Ismail, Nagore Eduardo, Kumar Rajiv
Abstract excerpt
Seborrheic keratoses are common benign epidermal lesions that are associated with increased age and sun-exposure. Those lesions despite harboring multiple somatic alterations in contrast to malignant tumors appear to be genetically stable. In order to investigate and characterize the presence of recurrent mutations, we performed exome sequencing on DNA from one seborrheic keratosis lesion and corresponding blood...
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