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Article

Influence of CYP2C9 and COX-2 Genetic Polymorphisms on Clinical Efficacy of Non-Steroidal Anti-Inflammatory Drugs in Treatment of Ankylosing Spondylitis.

Medical science monitor : international medical journal of experimental and clinical research - 12 Apr 2017

Wang Yu, Yi Xiao-Dong, Lu Hai-Lin

Abstract excerpt

BACKGROUND The aim of this study was to evaluate the relationships of CYP2C9 and COX-2 genetic polymorphisms with therapeutic efficacy of non-steroidal anti-inflammatory drugs (NSAIDs) in treatment of ankylosing spondylitis (AS). MATERIAL AND METHODS We enrolled 130 AS inpatients and outpatients in the Arthritis and Rheumatism Department of Peking University First Hospital and 106 healthy people getting routine...

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Share to Anti-Inflammatory Agents, Non-Steroidal
Share to Cyclooxygenase 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2C9

Share to Gene Frequency

Share to Polymorphism, Single Nucleotide

Share to Spondylitis, Ankylosing

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Source

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Identifiers

PMID: 28403136
DOI: 10.12659/msm.900271
PMCID: PMC5398431

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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