Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CYP2C9 polymorphism in non-steroidal anti-inflammatory drugs-induced gastropathy.

Journal of digestive diseases - 1 May 2008

Ma Juan, Yang Xiu Yan, Qiao Liang, Liang Liu Qin, Chen Min Hu

Abstract excerpt

OBJECTIVE: Non-steroidal anti-inflammatory drugs (NSAID) induce gastroduodenal mucosal injury and are metabolized by cytochrome P450 2C9 (CYP2C9). It is postulated that CYP2C9 genotype is associated with NSAID-induced gastropathy. This study aims to determine whether individuals with a CYP2C9 allele mutation are susceptible to NSAID-induced gastropathy. METHODS: A total of 109 patients diagnosed as having...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Inflammatory Agents, Non-Steroidal
Share to Aryl Hydrocarbon Hydroxylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2C9

Share to Gastrointestinal Diseases

Share to Gene Frequency

Share to Incidence

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 18419640
DOI: 10.1111/j.1751-2980.2008.00326.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CYP2C9 polymorphism in non-steroidal anti-inflammatory drugs-induced gastropathy.PMID 18419640Read ↗

An update on the pharmacogenomics of NSAID metabolism and the risk of gastrointestinal bleeding.Semantic proximity Read ↗

Genetic susceptibility to nonsteroidal anti-inflammatory drug-related gastroduodenal bleeding: role of cytochrome P450 2C9 polymorphisms.Semantic proximity Read ↗

Interaction of CYP2C8 and CYP2C9 genotypes modifies the risk for nonsteroidal anti-inflammatory drugs-related acute gastrointestinal bleeding.Semantic proximity Read ↗

Clinical and pharmacogenetic features of patients with upper gastrointestinal lesions at a multidisciplinary hospital: the role of nonsteroidal anti-inflammatory drugs.Semantic proximity Read ↗

Genetic predisposition to acute gastrointestinal bleeding after NSAIDs use.Semantic proximity Read ↗

Novel Use of Pharmacogenetic Testing in the Identification of CYP2C9 Polymorphisms Related to NSAID-Induced Gastropathy.Semantic proximity Read ↗

Allele variants of the cytochrome P450 2C9 genotype in white subjects from The Netherlands with serious gastroduodenal ulcers attributable to the use of NSAIDs.Semantic proximity Read ↗

Is cytochrome P450 2C9 genotype associated with NSAID gastric ulceration?Semantic proximity Read ↗

Risk factors of symptomatic NSAID-induced small intestinal injury and diaphragm disease.Semantic proximity Read ↗

CYP2C9 variants as a risk modifier of NSAID-related gastrointestinal bleedingSemantic proximity Read ↗

Review article: cellular and molecular mechanisms of NSAID-induced peptic ulcers.Semantic proximity Read ↗

Pharmacogenomics of non-steroidal antiinflammatory drug-induced gastrointestinal complicationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.